These are likely two different problems. With the Q80 motors (or any large out runner) the Mezon "Acceleration" time needs to be increased from the default. If not, upon rapid throttle opening, the motor speed will lag behind the ESC and a commutation error will occur resulting in a screech and motor stopping. A time of 1.1 - 1.5 sec. works. If too high the motor will accel too slowly, too low and it will stop upon rapid throttle opening. (Slowing the throttle opening at the TX with "servo speed" adjustment will work also.)
Sometimes settings that seem OK will toggle over to not with a prop change that increases load. The heavier or bigger (pitch / dia.) prop slows the motor accel to cause the problem. Best to check the accel with the rapid throttle opening trick on the ground whenever changing props.