Most two strokes are low compression so high octane is not of much use. With some of the higher compression 2 strokes it can be and is beneficial. The one thing I can guarantee is, if you are lean and or running hot, the higher octane will keep detonation from happening and that can save your engine. Believe it or not some of these little two strokes are 11.5:1
Put a pipe on a two stroke, run low octane in hot weather a little lean pushing it hard and wait for the detonation, even the low compression ones.