I've tried several of the trendy oils over the last few years ... from straight petroleum based through the synthetics and I can't say that any of them ran much different from the others as far as performance, reliability and smoothness were concerned.

Early this season I switched to Red Line Racing synthetic but mostly because it is far cheaper and more readily available than the previous oil I was using. Strictly a matter of convenience and economics. So far I have been very pleased with this change and I run it at 32:1 in every air cooled 2 stroke I own from airplane engines to lawn equipment. Just a personal preference and Yes I ran 50:1 and 40:1 for a season or more each in years past.