Matt, the Saito 100 factory settings on both needles are 1-1/2 turns out. On the low end setting, make sure that the throttle is closed and the throttle trim is zero before running the screw in, or just close the throttle manually which would be better. Open the low end 1-1/2 turns as well as the high end. Once started, with 1/8 increments turn the low end clock wise, in, and check idle and response. Between each adjustment run it up shortly and adjust again. You will notice the idle raising each time as well as smoothing out and getting quicker on the transition from low to full throttle. You should find it reaching a point of idle first and then, with further adjustment, the transition will work out. Joe

P.S. forgot, on the 2 strokes the low end setting is just the opposite. Turn it out to lean and in to richen.