The RF G2 should be very compatible and up to date (Another thing you might want to do is go to your video card mauf.'s website and download the latest Non-Beta driver...to), but if you buy an older version:
With RF Deluxe:
-Windows ME-XP Home-XP Pro. I use XP Pro on my Realflight Deluxe I had to go onsite and download one patch (fix) for the self executable files to auto run-then one to fix a Direct Draw issue I installed the Deluxe disc 1-then the add ons and then appplied the patch very easy and the original disc called for Direct X 6..I am using DX 8 latest version. The GeForce Nvidia card work well as ATI it seems-VooDoo as well..

Whew..I use the GeForce3 TI, not the newest but it does almost as good as the G4 Nvidia cards.