Deviation from thrust line
 

If I mount the engine such that the thrust line deviates from that which is drawn on the plan, what corrections, if any, should I make to compensate?

Obviously I would need to adjust the fuel tank position to center with the carb. But would I have to adjust the downthrust also? Say, for example, a low-wing airplane which calls for 2 degrees down thrust. If I move the thrust line farther up, would I need to decrease or increase the down thrust angle?

How about incidence angles, any changes necessary there?