Probably not, if both planes have the same engine and propeller.

However, as stated above, not all designs react the same to the same P and torque.
More draggy models, in the air and on the ground, seem to be more sensitive to those non-symmetrical forces.

I would say that, for each specific design, those angles are found by experimentation and flight-tests more than over the drafting table.

Once the prototype flies OK, the designer specifies those angles, incidences and CG location on the final drawings before the kit or ARF goes on into massive production.

The down-thrust angle tries to keep the pitch balance the same regardless the thrust force is high (full throttle) or low (idle).

The side-thrust angle is more of a compromise, because it tries to keep the yaw balance the same, while the thrust force on the right side of the propeller disk changes with AOA (P-factor), and the rolling-torque changes with rpm’s and speed of the airplane.