Yes! It definitely makes a difference.

Think of the props as the gears in your car...A short high pitched prop would be a high gear and a long flatter prop would be the lower gear.

With the lower gear you get quicker acceleration, lower top end speed, more braking at slow speeds, and more thrust.

With the higher gear acceleration goes down, top end speed goes up, braking at slow speeds goes down, and you lose thrust.

The 10x6 is about 5th gear in a 6 speed tranny...

Try an 11.5x4 which is just about 1st gear in 5 speed. A 12.25x3.75 would be 1st in a 6 speed...

My favorite is the APC 11.5x4! Perfect on my Thunder Tiger Pro .46 on my Profile Sledge. It's the one in my avator...