It appears that they indeed may work-if built properly. Since other 'air disturbing' devices, spoilers, airbrakes, flaps,elevons, etc. work when placed on a miniature aircraft, why not L.E. devices? The question, I think, then becomes-how to design and build them. In the case of the F16, what exactly did the plane do? I'm guessing if they're not exactly even, it would be no different then uneven flaps or ailerons out of trim-or built crooked.
I found some good stuff on Mike James site, think I'll give 'em a try!







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