Hi!
The reason the nut comes loose is probably that you do not tighten it enough. Loctite should not be used!!!!!
In my 37 years of flying R/C I have never myself encountered that the an alumium spinner nut has become loose. I have seen others though, but that has always been due to the fact that they have not used enough torque when installing the nut.
Those 4-way wrenches are no good!