I use CA a lot because it is fast. Getting some on your hands is inevitable. As others have noted, using tips and proceeding carefully, and planning the glue-up beforehand, are all important steps. I too use it also when I cut myself. A little hot when it cures but works like a charm. That said, it is expensive stuff so you have to be judicious in how and when you use it. I always have CA debonder on hand as well as accelerator, to control the behavior of the CA bead.

One of the things I like about it is that the thin soaks into wood very well, making the bond even stronger. What I typically do if strength is important is to use thin CA first to get into the wood, then thick to mate the surfaces. I use medium a lot to make glue fillets to reinforce formers to fuse in ARFs. The generic Bob Smith stuff is OK, but Zap glues are excellent.

This said, CA is not always ideal. It is strong, but also super brittle. Epoxy is better where you need strength with some flexibility, plus, epoxy will bond just about anything, whereas CA does not always bond certain materials. Also, it may be tempting to reinforce a part with glas and soak it with thin CA rather than epoxy. This works fine, except in cases where you want a smooth texture. Only epoxy will provide that.

I alsocombine CA with epoxy. I use CA to "tack up" the pieces, then use epoxy for the main job.