I own a few hundred Li-Po packs, all my jets use Li-Po's on ECU and Rx (2) (OK actually I have a Li-Fe in my Bobcat P-100Rx) I've been using Li-Po's since they were released in the early 2000's and other than showing people what can happen with charge abuse, I've never had an explosion or fire. I have blown up lots of duff/massive out of balance packs to learn what it takes.
You get lots of notice, so people that say they 'just exploded' are normally not telling you the whole story. Sound (the bags/heat shrink make lots of noise stretching) Smell...sweet odour is always present just before they go, temperature, warm cells are BAD!
I would not install Li-Po's where you couldn't quickly get them out-most of my packs have just HD Velcro and no strap. All easily accessible.
I have thousands of charge cycles and I'm very comfortable charging Li-Pos, but I use good clear chargers and always charge while i'm in the room. I monitor the cell voltages (easy on good chargers) I check when its first put on charge and 3-4 times during each charge. Cells that are more than 0.1V out of balance need careful consideration as they are probably never going to be right (if new) and need special attention if they were good balanced cells and have now got way out...Even one instance of huge abuse will reduce the life of a pack...

It comes down to you, your attention span and ability to be regimented on your routine.

Dw

Oh, I always connect the balancer..