Because "lift" is a function of three factors -

Wing area
Airfoil characteristics (shape, camber, angle of attack)
Speed (strictly velocity)

you can take your pick out of each of these to answer your question. To illustrate...

If you have a large wing area, the speed required to lift your 400 lb object will be slower. If you have a small wing area, the speed required will be greater.

The airfoil that you choose will have to be efficient within the speed "envelope" that you choose.

The airfoil/wingarea/speed will also determine the landing and takeoff speed required.

So a simple question with no simple answer.