While I was typing, RBACONS posted a good starting point and methods to get started. The answer to what he is talking about involves flying and adjustments.

Balance is your starting point.
Then you need to establish what prop you are always going to use, as it affects much of the later trimming process.
Then we start with the thrust, with right thrust and up or down thrust. From this point on it starts to get complicated, but often we can stop here until your flying skills improve with a good third or forth model. And frankly, many if not most never get past this point. They are perpetual beginners.