I have stripped out so many of those set screw I can not count. I have tried every hex wrench under the sun. They always seemed to strip out or for unknown reasons, be stripped when I wanted to take them out. I started using hex head screws in their place. You can tighten them a lot more and use a larger size hex wrench. Plus when you grind away the hardened surface of the wire, you can really lock them in place.
Another way I have seen is to cross drill the wire and use a piece of safety wire like a hair pin to hold every thing on if it comes loose.
Buzz.