I've never had Titebond fail me but I wouldn't use it to join wing halves or glue in a firewall. I use it for all kinds of things but there is one area you have to be careful with and that's laminations. It can warp structures when laminating. I built a stab for a small Sukhoi (sheeted stick frame) and when I glued the skin on, it warped like a dog's leg the next day. I started from scratch and built a new one with CA bonded skins and no problem.

carl