I use the same technique on my 2 stroke os 46 as one of the other guys recommended.

To set the low end I quickly throttle up. If the engine dies the low end is too lean so richen it up. If the engine seems to be 'catching' or hesitating before getting to high revs then it is too rich so you can lean it out a little. The revs should go up quickly and smoothly.

I know I am running too lean when I go full throttle, lift my nose so that it is pointing straight up and the engine dies. I richen the high end needle until this behaviour stops happening and I maintain steady revs

Ok take everything I wrote with a pinch of salt because I am a relative beginner! Hope it helps,

P.