Works both ways...
I use finger and thumb until it feels like I'm going to drop the transmitter... even my fingers don't reach the ground so I do what I have to to keep the box firmly in my hands... and I think I have more precision with thumb and finger, but I'm not a precision flyer, so who knows.
I do know that the difference is not enough to make me lose control or crash a plane (I do that all by myself).