The standard rule is that bigger planes fly better than small planes. The advantage of small planes is you can fly them in small spaces, typically at slower speeds with less risk of damage to the plane or any of the surrounding property or people.

For example, a 16 oz 3D electric can be hand launched vertically or normally in a small space. If it has a light wing loading, it can be flown quite slowly. You really would not want to do that with a 12 pound glow plane.

You can fly that 3D 16 oz plane in a baseball infield, perhaps flying around the bases. Again the larger plane would not likely be able to do that very easily.

The larger plane would be far less effected by wind or gusts.