A few years back during one of my PPG refresher courses, the topic of proper iso protection was addressed in the class. It was pointed out that the first stage (ie: particle filter) of a good mask is the part of the filter that traps the iso, not the carbon cartridge. I have been using these finishes since they were introduced, and by following the safety precautions, have managed to stay healthy. I have rules in place in the shop that prohibit the spraying of any iso containing materials in the open air. I also reccomend the use of a fresh air system for any top coats.
Believe me, paint containing iso can and will screw you up. PERIOD
If you do not have the means to protect yourself, then let a profesional spray for you.
Isocyanates can and will enter into the body through the eyes, any exposed skin or through the respiratory system. They are attracted to moisture and attach themselves to fatty cells in the body, where they remain...................

Ron Ballard