Yesterday am it's flight #2 for my 4*60 (also flight #2 for me on a glow model). Beautiful day, light wind, a little squirelly on takeoff, but all was well. On 2nd go-round, I notice a tiny black object dropping from the plane. Yup, it was a wheel. Crap [:@]! A little disconcerting to have to dump it in the grass on your 2nd flight! I flew out most of the tank, which was great as the plane just flys beautifully. Even did a few knife edges. Wasn't able to hold altitude tho - may need increased rudder throw or maybe I didn't have enough of a nose-up attitude before rolling (or maybe I need a bigger rudder).
Time to pay the piper. Brought it around nice and slow along the side of the paved runway and was able to gently drop it into the 6" grass. It flipped up and then settled back. Phew

! No damage, but no more flights as I didn't have a spare wheel.
Moral of the story - check the tightness of everything preflight! I had checked all the usuals, servos, linkages, etc, but not the wheels.