The only thing to watch out for is that the HIGH needle will affect the LOW if you do not have the butterfly closed enough. This can cause adjustment headaches. I know believe me.
Follow this procedure and you will not have any problems

Set the High for peak and back off a couple of hundred rpms.
Set the low for good transition and good idle (keep leaning till it won't transition then richen till it will)
NOW REPEAT THE ABOVE PROCEDURE and you are set to go. Remember Low will affect High that is why you repeat.
This is the same basic procedure to use on any gas engine. Ask Ralph for more details if you neeed.

Pull out the idle screw, there is no need for it anyway. If you get all turned around set both needles at 2 turns and repeat procedure. It should idle about 1800 give or take.

Try this on a few different engines a few dozen times and nothing to do with needles will every give you a problem again in your life.