Hmmm...I've been around, and into, MANY solvents over my life...at least what's left of it...maybe it's why I can be a grumpy old fart sometimes??? Lacquer thinner, acetone, denatured alcohol, mineral spirits, toluene, MEK, xylene are the bulk of my exposure with lacquer thinner and mineral spirits being the most heavily used. I have found that some things require a special solvent in order to do what you want to do. I try to keep skin contact and inhalation of vapors to a minimum but there is no way to totally eliminate both unless you are wearing a bio-hazard suit. IMO, using any solvent in a well ventilated area and with gloves basically constitutes no real health dangers. No matter what you do or don't do...you're gonna die!