You need to get your engine to a base tuning. We do this for our RC cars. For the TT46Pro, the high speed needle is usually opened about 2-2.5 turns from fully closed, the low speed needle I am not too sure now but its about 3 turns out max when the throttle is fully closed. If your engine picks up sluggishly then its usually (assuming your prop is the correct one) your low end is too rich. You need to close it about 1/4 turn at a time till it picks up smoothly. Once its smooth then you can perhaps open it just a touch maybe 1/8 turn only. This ensures your engine will not overheat a bit.

From experience I have noticed that if you have gotten the high speed needle right and the engine seems to be really hot then open up the low end.

My TT46 starts with a backflip of the spinner.