RE: thrust to weight?
Don't know if you have advanced past the CAD stage of things. But I'll toss this out for what it's worth.
My Kyosho T33 develops about 14 oz of static thrust. The t/w for this plane is .35, the wing loading is ~18.5 oz/sq.ft. and the air frame is "draggy". The fan is a stock Ky unit, power input is 99 w/lb. The airfoil is a Clark Y, about 12% at the root, thins toward the tip. Hand launch is a non issue, just a shove and it is gone, top speed of perhaps 45 mph, generally a nice flying plane to fly in a small area.
My GWS A10 weighs in at 23.5 oz, the thrust might be 10 oz total for t/w of .42. With a power input of 120 w/lb, very easy hand launch, can be flown very fast but slows nicely for landing. The airfoil is an undercambered something or other, maybe a Clark. The wing loading is about 16 oz/sq.ft.
The previous comments about wing loading and drag are valid. The choice of air foil will come into play as well.
An EDF with a t/w that approaches unity would be a blast to fly, allowing true verticals. Further I would think a t/w = .3 is an absolute minimum, any thing less will have to be a floater. If you want to ROG, I would guess a t/w of .5~.7 would be a good target. But without retracts the air frame drag will be very high, keeping the top speed down.