Depends on what you mean by 'a few degrees' and 'major'.

Will it impact how the plane flies? Yes, absolutely. Will it make the plane unflyable? PROBABLY not if it's truly only a 'few degrees'

Most likely, if it's not bad, a little trim in flight will probably null it out. To be sure, however, we'd really need to see a picture, or at least get a better idea of how far off it is. Can you set the plane down level, and measure table to stb tip on each side, and tell us how far apart the measurements are?