remake all of the setup by sequence

1 start your engine let it warm
2 open your engine at full throttle and set the high end to reach the max rpm and after turn the needle 4 click back to have a little rich high end
3 now try to set your low end and let your engine turning at idle and see wath happen.
try to run it at 2200 rpm
if the transition idle to max rpm is plenty of smoke your low end is to rich turn the screw clockwise

I hope this help you

and let me know wath happen