For my setup,

ESC is a Schulze 32.55K - 250 flights no issues
Plettenberg 25-13 motor - 210 flights or so, never had to touch it No gearbox, no maintenance.
Batteries - around 50 cycles on the 5300 packs, who knows how many more I will get.....but they remain in perfect balance.

My friend Adam (who posts here) recently did a capacity check on his 5s3p 6000 Prolite packs and noticed approximately 3% capacity loss in 40 cycles. If that trend is linear they should be good to at least a 10-15% loss before replacement which puts them in the range of 150-200 cycles....

I dont think previous generation packs were good enough to get close to those numbers in our application so it will be a bit yet before many people really start to cycle these packs out.

As long as things keep cool (especially the motor and batteries) I have found my setup to be basically 100% trouble free, but I was very meticulous intially about knowing the temperatures under different conditions.