No, but if you mean "tightening" a prop nut, it could damage the prop, especially if it's wooden. After the nut is snug, tighten it about 3/4-1 turn more, depending on the material the prop is made from. Composite props will not let you tighten a nut as tight as wooden props will. It's wise to check the tightness of the nut on wooden props occasionally.

Dr.1