I have successfully used the Cline regulators in a single tank setup on a Me110. One item of note: the Cline regulators do not provide a pressure feed to the carburetor. They work so as to make the carb act as if it is drawing fuel from a distance equal to the distance from the regulator to the carb. In order to make my engines (Thunder Tiger .46) run reliably without pressure at the carb, I had to put restrictors made of brass tubing in the carb throats to increase the suction draw.