You really want to do all the settings physically to set the hardware on the airplane as nearly correct as possible. You don't want to use the radio's capability to modify end points or change servo centering or increase/decrease throws until you have the hardware set up as good as you can get it.

If you don't setup the airplane worth spit, the radio may be able to cover the mess, but........ I've had to help a number of people who're members of the "I bought that expensive radio so I don't have to know how to actually setup a model worth spit" club fix "problems with their crummy engines". Learn to rig your connections "manually" and you'll bypass a bunch of lousy flying models that aren't lousy flying models at all.

I helped one of those guys just the other day whose elevator "was designed wrong". When I suggested that the connector rod was too short (and it's servo wasn't square either) he wanted to fix it with his radio. Since he'd already "fixed it" with the radio when he "built" the model, and the radio was all out of "fixing" adjustment, he was in a fix. After squaring the servo/connecting rod, adjusting the rod to length, and moving the rod connection out the elevator horn from the inside hole to the outside hole (he knew the model was designed poorly because the thing was way too sensitive to elevator input), he decided that the problem was that his expensive radio wasn't good enough..... chuckle..... anyway.......

Once you have the throttle setup "the old way", your computer radio will tune the sucker excellently well, and you won't be stalling the throttle servo or flying without full throttle or with a motor that "won't idle down all the way". I've seen two models in the last month that "wouldn't idle down enough" that just needed the hardware rigged correctly.

there is more.......