Ryan, if you're really just wondering about stuff..... (I ALWAYS AM)

The way airplanes are designed is to start with what you want to do with them. Skipping past a lot of other decisions...... and after figuring out how big a wing you're going to need, and what airfoil you plan to use, you take the probable weight and look up the stats on your airfoil.

You'll find what AOA that airfoil will be when it's carrying your design load at your design speed. And you'll then draw your airfoil into your sideview blueprint so it'll be at that AOA when the fuselage is at it's least draggy orientation.

You usually want the wing to operate most efficiently when the fuselage is operating most efficiently etc etc......

Some airfoils will be relatively close to ZERO AOA at their operating speed, so will be zero incidence in the fuselage. Cambered ones will have more incidence.