Pretty much anything is better than urethane glue. That would be my last choice as a hinge glue. Yes it holds well but so does everything else. Who wants to have to keep coming back over and over to keep wiping out the access glue, due to the expansion. With other glues there isn't worry that the hinge will be pushed out by the expanding urethane. I have professional experience with these glues and urethane is great glue but I personally don't care to use it on hinges.

As far as putting CA in the hole before gluing. As stated before CA will seal the fibers of the wood up so the glue you are going to use can't soak into the wood. Really the only time I can think that you need to " harden " a hole is when you are going to put screws in a soft wood, as they might pull out under pressure. This is the only real for hardening holes. The glue you use to put the hinges in with will harden the holes sufficiently.