That said, I've had CA joints fail because of brittleness of CA relative to epoxy.
Gee, your planes must vibrate a lot. I've never experienced that type of failure of a CA joint.

Hardworking joints like firewall, landing gear mounting plate, joining wing halves, wing-mount blocks--these get epoxied and cured overnight.
Ah...no. About 15 years ago, I built a giant Stinger usnig CA exclusively. Through three owners it's still flying with no structural problems.

Structural joints that will end up being covered over with film or glass are less critical in terms of joint strength than those that depend on glue strength alone. The monokote/ultracote skin is a wonderful stress distributor.
It may be, but I don't rely on the covering to hold my framework together in the air.

All that being said, ANY joint should be as mechanically tight as possible BEFORE the glue is ever applied.

Dr.1