I adjust my engines far less than my 2S flying friends who seem to be constantly trying to burn out their engines.
I have little problems adjusting engines also, and have no problemws with either two or four stroke. I think this has a lot to do with experiance. IMO a lot of people switch to four stroke when they get to a certain level of experiance and thus experiance less problems. Some work with both and don't notice a dimes worth of differance. Four strokes do have less problems with fuel tank placement, but that is simply because they have smaller carbs which helps to improve fuel draw.