The main drawback is it may tend to run rich, especially at idle, and it may be hard to keep the plug lit.
the engine on my cloud dancer is inverted and it is a pita sometimes. I couldnt keep it running long enough to do anything. I finally had my friend hold it upsidedown, (motor right side up) and tuned it that way to get a decent starting point. If you can, lean the low end a bit it will help. It is a diffrent critter when they are upside down. Once you get it tuned right, it is just as solid as right side up. Plugs with the idle bar do not help much. I tried 3 diffrent types. So unless you want to , I wouldnt bother with that. Just go with the onboard driver.