Are you trying to figure out how long you will be able to fly? Or just if the motors will operate? If the LiPo has a C rating that is high enough to handle the amp draw of the two motors running simultaneously, and the motors are rated to handle the 11.1 volts the battery has to deliver, and your ESC's are rated to handle the amp draw of both motors running at the same time and has a LiPo auto cutoff function.......etc..... you should be fine. A little more specifics would help. The C rating of the battery, are you indeed trying to run both motors at the same time off of the one ESC, what brand is the ESC, what is the amp draw range, continuous current and max. burst of the motor?