I started off with the Avistar 3 years ago, and have the 46FX on the nose. First off, with this engine, this plane will scream, even with the ground landing equipment. It also gives it a tighter learning curve, because of the semi-semetrical (sp?) wing, so be ready, but your best bet is to GET AN INSTRUCTOR. I tried to fly one time in the beginning without my Instructor, and that was the day that I crashed it good. But I repaired it and kept going.
If you're getting the RTF with the aluminum tube and metal straps for the main wing, be sure that you check the screw alignment and ca the holes! If you're getting the ARF, I would suggest glassing the wing joint with fiberglass tape and epoxy, as this will add more strength for when you get into aerobatic practice.
As for starting off learning to fly on water, I must say to pay attention to the folks up top that have given you sound advice on this angle. A seaplane is nice and it gives you more places to fly, but it is a different world than doing the ground side. Although, if it has snowed in your area, or it will be, you can forego skis and fly off them in powder.
With all that said, good luck and have a happy holiday!