To tune your DA50R lean the high speed needle for peak rpm, then richen it to loose 200 rpm.
lean the low speed needle til the motor balks when you flip the throttle from idle to wide open then richen it till you get a good transition.
When breaking in a new motor it should be a little rich but not to rich or it will get all carboned up the rings will stick your plug will get all carboned up, not good.
I would not run it with the high needle all the way out, asking for trouble.
the manual says high speed needle 1 & 7/8 turn out. low speed needle 1 & 5/8 turn out.

If in doubt call DA they will tell you what to do, They are very help ful