I became totally blind in one eye shortly after I had learned to fly RC and flew that way for about 5 years. Fortunately, my sight has been restored in that eye with surgery and it is surely easier with two eyes. When I was flying with just one, I could only fly on sunny days as I needed the shadow on the ground to tell me when to flare for the landings. Needless to say, I broke a few props and bent some landing gear during that time.