Most debonders on the market today are either made from nitromethane or acetone. Many times, the debonders are a blend of both of these solvents. These blends seem to work better for removing cured CA from skin and they are the safest two solvents to use topically for this purpose in small amounts. Nitro always sounds nasty and it is, but only if you try and compress the liquid. Other than that, it is not volatile, practically non-toxic, and with a flash point of98°F is not dangerous to have around the shop. There is another solvent that dissolves cured CA that some manufacturers use and that is Acetonitrile. You will see it labeled sometimes as "Safe water-based chemistry." It most certainly is not. Acetonitrile is better known as methyl cyanide. If ingested, this chemical can easily kill you.