I am running a SuperTigre GS40 on E85 in a Super Sportster. I add 15% nitro and the oil is 18% blended at 80/20 synth/castor. It runs virtually identical to glow fuel with the exception of about 1 to 200 rpm's lost on the top. I have to run an OS F plug in it to get the idle low and smooth but otherwise it runs great. I also had to lean the HS needle about 1/2 turn and I didn't pay attention to how much I leaned the low needle but it wasn't much, maybe a 1/4 turn or so. It is just a tiny bit rich in the mid range but not unacceptable. Overall it's been a great little project.