Few of us fly, or drive with a full open throttle all the time.
Speak for yourself
The volume of the boost ports and crank case also play into the equation. The engine book put out by MAN is very comprehensive in explaining how all these systems work with each other. I just finished reading it and while being a pretty decent hand in a machine shop have decided to hold off on whittling away at a motor just yet without fully understanding which mod will give me the biggest bang for my work.