I foresee no structural problems, things to note when flying; it will have more drag, but then the real thing is hardly a Spitfire, to effectively use them you will need plenty of elevator to keep the AOA up when flying slow, lots of rudder too, as you can't use aileron to pick up a wing at the speeds it will be capable of. And an engine capable of turning a large prop of reasonably fine pitch, to be an efficient match to the speed profile of the model. You may find that some sort of flap arrangement might be useful too.
Evan, WB #12.