The 2-stroke V-twins in the Banshees and snowmobiles, etc. all use two seperate carbs to feed the two cylinders (some are even fuel injected). The carbs feed directly into each cylinder. The crankcase is not used like it is in RC Nitro engines.
I don't know all of the physics behind it, but I'm with supertib on this one. I don't think the V-twin nitro will work, and if it does, it'll likely run quite poorly.
-Howard