Once I got it running just how I want it and it flies good, I leave it be. Unless there is a drastic change in weather that may cause my engine to run lean, then I would usually richen it a few clicks and return it back to my previous setting after I'm done for that day. Air is denser when it's cold and it could cause your engine to lean out, and if you were already at peak performance then the little bit may cause a dead stick, thats why I richen it a little bit on colder days.

But being in San Diego, CA....... our weather is pretty constant.