Cavitation on an orbit clunk is possible on larger engines.
I have used them with total success on Wren 44's and 54's.
It is all about restriction, if the flow is restricted through the element (of any filter) then the pressure between the filter and the pump drops.
This causes trapped gas in the fuel to release into the fuel line in the form of micro bubbles.
So with any filter that cannot pass the flow rate required, it is possible to get de-gassing or cavitation.

Paul