In that case we clearly have a mechanical problem with the contact either in my connectors or in your buddy socket. The last but very rare possibility is a defect in the USB interface.

Please move the connctors a little and check if things improve.
Do you have a chance to test another radio with that connector, maybe at a friends PC and radio?

The last chance is a possible defect in the PPM code of your radio. What happens if you connect a receiver and servos? Do they move correctly?

Are there any other USB devices connected to your computer?

Cheers - wolfgang