Reflex flight sim
That's good news. In that case we only have 2 possibilities left: connectors and drivers.
Please disconnect any other USB device from your computer. Go to control panel, system, hardware, hardware manager - input devices (Human interface device) and right-click to the HID device left. Select UPDATE DRIVER and direct the driver search to c:\program files\reflex. Pless ok for 10-20 times ...
Thisway, you are directing the input through the interface exactly to this particular driver and not through the standard Windows HID driver.
Please try this and let me know what happens.
Cheers - wolfgang