RE: Designing and building!!!
I have scratch-built using the basic design parameters as a starting point. After sorting out the power train issues, I have a configuration that flies very well. My drawings are pretty simple and easy to fabricate using hand tools. I personally prefer balsa construction and built-up wings. There are other materials and methods that will produce excellent results.
I would recommend keeping things very simple at first and on the small side. Ships in the 16-25 oz range can be built and powered economically and are easy to see in flight and able to handle a moderate wind with no problems. Once you have a flying model, it is easy to make incremental changes that improve performance.